General
Preferred name
BUTOXAMINE
Synonyms
Butoxamine hydrochloride ()
Butaxamine (hydrochloride) ()
Butoxamin (hydrochloride) ()
Butaxamine ()
Butaxamina ()
BW- 64-9 ()
BW-64-9 ()
BW 64-9 ()
NSC-106565 ()
BW 64 9 ()
Butaxamine hydrochloride ()
P&D ID
PD014550
CAS
2922-20-5
5696-15-1
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
beta-2 selective adrenergic antagonist
(GtoPdb)
DESCRIPTION
Butaxamine (Butoxamin) hydrochloride is a specific ¦Â2-adrenergic receptor blocker. Butaxamine hydrochloride inhibits the decreases in urine volume in ethanol-anesthetized, water-diuretic rats[1].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
ChEMBL Drugs
DrugMatrix
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
25
Molecular Weight
267.18
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
1
Aromatic Ring Count
1
cLogP
2.51
TPSA
50.72
Fraction CSP3
0.6
Chiral centers
2.0
Largest ring
6.0
QED
0.86
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Adrenergic Receptor
Pathway
GPCR/G protein
Neuronal Signaling
Source data
