General
Preferred name
Canrenoic acid
Synonyms
Canerenoate ()
Potassium aldadiene ()
Canrenoic acid potassium salt ()
potassium canrenoate ()
Soldactone ()
Canrenoate (potassium) ()
Aldadiene (potassium) ()
SC-14266 ()
CANRENOATE POTASSIUM ()
CANRENOATE ()
NSC-757789 ()
Canrenone free acid potassium salt ()
Canrenoate de potassium ()
Kanrenol ()
Spiroctan-M ()
Canrenoato de potasio ()
Acide canrenoique ()
Acido canrenoico ()
P&D ID
PD014514
CAS
2181-04-6
4138-96-9
Tags
available
drug candidate
drug
Drug Status
approved
withdrawn
investigational
Max Phase
3.0
Drug indication
Cardiovascular disease
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Canrenoate potassium (Soldactone) is a synthetic pregnadiene derivative with anti-aldosterone activity. (TargetMol Bioactive Compound Library)
Compound Sets
12
ChEMBL Drugs
CHEMBL1371200
CHEMBL1616951
Drug Repurposing Hub
DrugBank
DB09015
DrugBank Approved Drugs
DB09015
DrugCentral
477
DrugCentral Approved Drugs
477
MedChem Express Bioactive Compound Library
HY-B1582A
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
potassium-canrenoate
TargetMol Bioactive Compound Library
T3096
External IDs
63
Properties
(calculated by RDKit )
Molecular Weight
358.21
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
0
cLogP
3.89
TPSA
74.6
Fraction CSP3
0.73
Chiral centers
6.0
Largest ring
6.0
QED
0.8
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Mineralocorticoid Receptor
NR3C2
Indication
edema
MOA
Mineralocorticoid Receptor Antagonist
Pathway
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Endocrinology/Hormones
Source data