General
Preferred name
HYDROXYAMPHETAMINE
Synonyms
HYDROXYAMPHETAMINE HYDROBROMIDE ()
Paredrine ()
Hydroxyamphetamine,(+/-) ()
hydroxyamfetamine ()
4-hydroxy Amphetamine (hydrochloride) ()
Hydroxyamphetamine hbr ()
Hyroxyamfetamine hydrobromide ()
Hydroxyamphetamine hydrobromide component of paremyd ()
NSC-61065 ()
Phenol, 4-(2-aminopropyl)-, hbr ()
Hydroxyamfetamine hydrobromide ()
Hydroxyamfetamine hbr ()
Norveritol ()
Hidroxianfetamina ()
Dl-4-hydroxyamphetamine ()
Dl-p-hydroxyamphetamine ()
Pulsoton ()
Racemic p-hydroxyamphetamine ()
Phenol, p-(2-aminopropyl)- ()
P-hydroxyamphetamine ()
NSC-170995 ()
P&D ID
PD014502
CAS
306-21-8
1518-86-1
140-36-3
6078-07-5
103-86-6
876-26-6
Tags
available
drug
Approved by
FDA
First approval
1969
Drug indication
Horner syndrome
Drug Status
approved
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Hydroxyamphetamine is a derivative of amphetamines. Hydroxyamphetamine is intended mainly as local eye drops for diagnostic purposes. It is an indirect acting sympathomimetic agent which causes the release of norepinephrine from adrenergic nerve terminals, resulting in mydriasis.
(Enamine Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
16
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine Bioactive Compounds
Enamine BioReference Compounds
Ki Database
NCATS Inxight Approved Drugs
NPC Screening Collection
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
62
Molecular Weight
151.1
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
1.28
TPSA
46.25
Fraction CSP3
0.33
Chiral centers
1.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
