General
Preferred name
DETOMIDINE
Synonyms
DETOMIDINE HYDROCHLORIDE ()
Domosedan ()
MPV-253 AII ()
Detomidine HCl ()
Detomidine (hydrochloride) ()
MPV 253AII ()
Detomidina ()
P&D ID
PD014466
CAS
90038-01-0
76631-46-4
Tags
available
drug
drug candidate
Approved by
FDA
Drug Status
approved
vet_approved
investigational
Drug indication
Sedative-Hypnotic
Analgesic (veterinary)
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
INDICATION Used as a large animal sedative, primarily in horses.
Compound Sets
14
AdooQ Bioactive Compound Library
A10298
Cayman Chemical Bioactives
17853
38583
ChEMBL Drugs
CHEMBL2106210
CHEMBL2110829
Drug Repurposing Hub
DrugBank
DB11556
DrugBank Approved Drugs
DB11556
DrugCentral
5674
DrugMatrix
MedChem Express Bioactive Compound Library
HY-B0163A
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
detomidine-hcl
TargetMol Bioactive Compound Library
T6464
The Spectrum Collection
External IDs
44
Properties
(calculated by RDKit )
Molecular Weight
186.12
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
2
cLogP
2.62
TPSA
28.68
Fraction CSP3
0.25
Chiral centers
0.0
Largest ring
6.0
QED
0.77
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Adrenergic Receptor
??2 catecholamine receptors
ADRA2A
Pathway
GPCR/G protein
Neuronal Signaling
Indication
sedative
MOA
Adrenergic Receptor agonist
Source data