General
Preferred name
TERPIN
Synonyms
cis-Terpin hydrate ()
TERPIN HYDRATE ()
Terpin Monohydrate ()
4-p-Menthan-1,8-diol ()
cis-p-Menthan-1,8-diol ()
Terpin (hydrate) ()
P&D ID
PD014460
CAS
2451-01-6
565-48-0
Tags
natural product
drug
available
Drug Status
experimental
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
INDICATION Terpin hydrate is used in the treatment of acute and chronic bronchitis, pneumonia, bronchiectasis, chronic obstructive pulmonary disease, infectious and inflammatory diseases of the upper respiratory tract.
MOA Terpin hydrate improves mucociliary function by working directly on the bronchial secretory cells in the lower respiratory tract to liquify and facilitate the elimination of bronchial secretionsas well as exerting a weak antiseptic effect on the pulmonary parenchyma. It is thought to increase the amount of fluid in the respiratory tract, which increases the flow and clearance of local irritants and as well as reducing the viscosity of mucus [T34].
Compound Sets
7
DrugBank
DB13163
DrugBank Approved Drugs
DB13163
DrugCentral
2604
DrugCentral Approved Drugs
2604
MedChem Express Bioactive Compound Library
HY-B1063
NPC Screening Collection
TargetMol Bioactive Compound Library
T0910
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
172.15
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
0
cLogP
1.7
TPSA
40.46
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
6.0
QED
0.63
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data