General
Preferred name
NETILMICIN
Synonyms
SCH-20569 ()
Netillin ()
Netromycin ()
SCH-20569 (sulfate) ()
Certomycin ()
NETILMICIN SULFATE ()
SCH-20569 (sulfate)Certomycin ()
Netilmicin ()
Netromicine ()
netilimicin sulfate ()
Netilmicin (sulfate) ()
Netilmicin sulphate ()
SCH 20569 ()
NSC-759586 ()
Netira ()
Netilimicin (sulfate) ()
P&D ID
PD014420
CAS
56391-57-2
56391-56-1
Tags
natural product
drug
available
Approved by
FDA
First approval
1983
Drug Status
investigational
approved
withdrawn
Drug indication
Bacterial infection
Antibacterial
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Netilmicin is a semisynthetic derivative of , with activity against Gram-negative bacteria . It belongs to the aminoglycoside class of antibacterial compounds.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
17
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Natural product-based probes and drugs
NPC Screening Collection
Other bioactive compounds
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
54
Molecular Weight
475.3
Hydrogen Bond Acceptors
12
Hydrogen Bond Donors
8
Rotatable Bonds
8
Ring Count
3
Aromatic Ring Count
0
cLogP
-3.2
TPSA
199.73
Fraction CSP3
0.9
Chiral centers
11.0
Largest ring
6.0
QED
0.18
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Anti-infection
Target
Antibacterial
antibiotic
Bacterial
Indication
gram-negative bacterial infections
MOA
protein synthesis inhibitor
ATC
J01GB07
S01AA23
Biosynthetic Origin
Carbohydrate (Aminoglycoside)
Therapeutic Class
Antimicrobial
Antibiotics
Source data
