General
Preferred name
TERGURIDE
Synonyms
Teluron ()
Tergurida ()
P&D ID
PD014387
CAS
37686-84-3
106347-60-8
Tags
available
drug
Approved by
PMDA
Drug indication
Pulmonary arterial hypertension
Drug Status
approved
experimental
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Terguride is an ergoline type serotonin receptor antagonist/dopamine receptor agonist. (GtoPdb)
Compound Sets
10
Cayman Chemical Bioactives
42028
ChEMBL Drugs
CHEMBL73151
Drug Repurposing Hub
DrugBank
DB13399
DrugCentral
2601
DrugCentral Approved Drugs
2601
DrugMAP
DMZNFPG
Guide to Pharmacology
56
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
External IDs
25
Properties
(calculated by RDKit )
Molecular Weight
340.23
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
2
cLogP
2.93
TPSA
51.37
Fraction CSP3
0.55
Chiral centers
3.0
Largest ring
6.0
QED
0.9
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
member
MOA
5-HT2A Antagonists
5-HT2B Antagonists
Prolactin Secretion Inhibitors
dopamine receptor agonist, serotonin receptor antagonist
Indication
Parkinson's Disease
Target
ADRA1A, ADRA2A, ADRA2B, ADRA2C, DRD2, DRD3, DRD4, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C
Source data