General
Preferred name
GAMMA-AMINO-BETA-HYDROXYBUTYRIC ACID
Synonyms
aminohydroxybutyric acid ()
4-Amino-3-hydroxybutyric acid ()
3-Hydroxy-GABA ()
aminohydroxybutyric-acid ()
4-Amino-3-hydroxy-butyric acid ()
Gamibetal ()
NSC-40244 ()
Gabomade ()
DL-4-Amino-3-hydroxybutyric acid ()
P&D ID
PD014323
CAS
924-49-2
Tags
available
drug
Drug indication
Discovery agent
Drug Status
approved
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
DL-4-amino-3-hydroxybutyric acid is an inhibitor of [3H]GABA binding to postsynaptic receptors.
(Enamine Bioactive Compounds)
DESCRIPTION
Gamibetal (4-Amino-3-hydroxybutyric Acid) is used as a chiral reagent in the synthesis of antiepileptic and hypotensive drug GABOB and analogues. Also used in the preparation of HIV-1 inhibitors derived from Betulinic Acid (B330250).
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
ChEMBL Drugs
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
Enamine Bioactive Compounds
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
33
Molecular Weight
119.06
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
0
Aromatic Ring Count
0
cLogP
-1.22
TPSA
83.55
Fraction CSP3
0.75
Chiral centers
1.0
Largest ring
0.0
QED
0.43
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
HIV-1
Endogenous Metabolite
Pathway
Microbiology/virology
Proteases/Proteasome
Metabolic Enzyme/Protease
Source data
