General
Preferred name
SUPLATAST
Synonyms
SUPLATAST TOSYLATE ()
SUPLATAST TOSILATE ()
IPD 1151T ()
IPD-1151T ()
Suplatast (Tosilate) ()
IPD-1151T, Suplatast Tosilate ()
Tosilato de suplatast ()
Tosilate de suplatast ()
Ipd ()
Suplatast ion ()
Suplatast cation ()
Suplatast (tosylate) ()
P&D ID
PD014303
CAS
94055-75-1
94055-76-2
Tags
available
drug
Drug indication
Allergy
Drug Status
approved
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor which can inhibit both IL-4 and IL-5 production from Th2 cells and suppress IgE synthesis. Suplatast Tosilate is an anti-allergic agent. Suplatast Tosilate has antiasthmatic, anti-inflammatory and antifibrotic activity[1][2][3][4].
PRICE 29
DESCRIPTION Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug with an IC50 above 100 ??M, inhibiting both IgE production and the synthesis of IL-4 and IL-5.
DESCRIPTION Suplatast Tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM. (BOC Sciences Bioactive Compounds)
DESCRIPTION Th2 cytokine synthesis inhibitor; antiasthmatic (Tocriscreen Total)
DESCRIPTION Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug with an IC50 above 100 μM, inhibiting both IgE production and the synthesis of IL-4 and IL-5. (TargetMol Bioactive Compound Library)
Compound Sets
17
AdooQ Bioactive Compound Library
A10881
BOC Sciences Bioactive Compounds
suplatast-tosylate-cas-94055-76-2-item-84-79871
Cayman Chemical Bioactives
30316
ChEMBL Drugs
CHEMBL115435
CHEMBL1180156
DrugBank
DB19138
DrugCentral
2545
DrugCentral Approved Drugs
2545
DrugMAP
DMOGREH
DrugMAP Approved Drugs
DMOGREH
DrugMatrix
MedChem Express Bioactive Compound Library
HY-17002
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
suplatast-tosilate
TargetMol Bioactive Compound Library
T0117
The Spectrum Collection
Tocriscreen Total
External IDs
38
Properties
(calculated by RDKit )
Molecular Weight
328.16
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
10
Ring Count
1
Aromatic Ring Count
1
cLogP
1.67
TPSA
67.79
Fraction CSP3
0.56
Chiral centers
1.0
Largest ring
6.0
QED
0.64
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Interleukin
Th2 cytokine
Interleukin Related
Interleukins
MOA
IL Receptor inhibitor
Pathway
Immunology/Inflammation
Source data