General
Preferred name
OLEANDOMYCIN
Synonyms
OLEANDOMYCIN PHOSPHATE ()
E704 ()
Oleandomycine ()
Oleandomicina ()
Oleandomycin phosphate (1:1) ()
Matromycin ()
P&D ID
PD014271
CAS
7060-74-4
3922-90-5
Tags
available
drug
natural product
drug candidate
Drug Status
vet_approved
approved
investigational
Max Phase
2.0
Drug indication
bacterial disease
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Oleandomycin is a 14-membered macrolide antibacterial compound, originally isolated from Streptomyces antibioticus.
(GtoPdb)
DESCRIPTION
Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes[1][2].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
Guide to Pharmacology
NPC Screening Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
38
Molecular Weight
687.42
Hydrogen Bond Acceptors
13
Hydrogen Bond Donors
3
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
0
cLogP
1.91
TPSA
165.98
Fraction CSP3
0.94
Chiral centers
18.0
Largest ring
14.0
QED
0.27
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Anti-infection
Target
antibiotic
Bacterial
Source data
