General
Preferred name
HYDROXYFLUTAMIDE
Synonyms
2-hydroxy Flutamide ()
2-Hydroxyflutamide ()
HFT ()
Hydroxyflutamide (Hydroxyniphtholide) ()
Hydroxy-flutamide, SCH-16423 ()
.alpha.-hydroxyflutamide ()
Hydroxy-flutamide ()
P&D ID
PD014247
CAS
52806-53-8
Tags
available
probe
drug
Drug indication
Prostate cancer
Drug Status
investigational
approved
Max Phase
Phase 2
Probe info
Probe type
calculated probe
Probe sources
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
8
No orthogonal probes found
Similar probes
1
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
3
Organisms
0
Compound Sets
19
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugMAP
DrugMAP Approved Drugs
Enamine BioReference Compounds
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
NURSA ligand set
Probe Miner (suitable probes)
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Properties
(calculated by RDKit )
Molecular Weight
292.07
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
2.32
TPSA
92.47
Fraction CSP3
0.36
Chiral centers
0.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Endocrinology/Hormones
Vitamin D Related/Nuclear Receptor
Target
Androgen Receptor
AR
Adrenergic Receptor
MOA
Androgen Receptor antagonist
Therapeutic Class
Anticancer Agents
Source data
