General
Preferred name
DELAPRIL
Synonyms
DELAPRIL HYDROCHLORIDE ()
indalapril ()
Alindapril Hydrochloride ()
Delapril Hydrochloride ()
CV 3317 ()
Delapril (hydrochloride) ()
Adecut ()
REV 6000A ()
Delapril hcl ()
REV-6000A ()
P&D ID
PD014193
CAS
83435-66-9
119543-18-9
83435-67-0
Tags
available
drug candidate
drug
Drug indication
Cardiovascular disease
Drug Status
approved
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Delapril hydrochloride is an angiotensin-converting enzyme (ACE) inhibitor for the treatment of cardiovascular diseases[1].
PRICE
54
DESCRIPTION
Delapril Hydrochloride is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive effect.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Delapril hydrochloride (indalapril) is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhibit angiotensin-converting enzyme (ACE), hence blocking angiotensin I to angiotensin II conversion.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
BOC Sciences Bioactive Compounds
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
43
Molecular Weight
452.23
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
11
Ring Count
3
Aromatic Ring Count
2
cLogP
2.61
TPSA
95.94
Fraction CSP3
0.42
Chiral centers
2.0
Largest ring
6.0
QED
0.51
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
ACE
ACE,RAAS
Angiotensin-converting Enzyme (ACE)
Indication
hypertension
MOA
angiotensin converting enzyme inhibitor
Pathway
Metabolic Enzyme/Protease
Endocrinology/Hormones
Source data
