General
Preferred name
DELAPRIL
Synonyms
DELAPRIL HYDROCHLORIDE ()
Alindapril Hydrochloride ()
CV 3317 ()
indalapril ()
Delapril?Hydrochloride ()
Delapril (hydrochloride) ()
Adecut ()
REV-6000A ()
REV 6000A ()
Delapril hcl ()
P&D ID
PD014193
CAS
83435-66-9
119543-18-9
83435-67-0
Tags
available
drug candidate
drug
Drug indication
Cardiovascular disease
Enzyme Inhibitor (angiotensin-converting)
Antihypertensive
Drug Status
investigational
approved
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Delapril Hydrochloride is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive effect.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
BOC Sciences Bioactive Compounds
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
42
Molecular Weight
452.23
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
11
Ring Count
3
Aromatic Ring Count
2
cLogP
2.61
TPSA
95.94
Fraction CSP3
0.42
Chiral centers
2.0
Largest ring
6.0
QED
0.51
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Endocrinology/Hormones
Metabolic Enzyme/Protease
Target
ACE
Angiotensin-converting Enzyme (ACE)
ACE,RAAS
Indication
hypertension
MOA
angiotensin converting enzyme inhibitor
Source data
