General
Preferred name
FLUPROSTENOL
Synonyms
Fluprostenol ()
(+)-Fluprostenol ()
FLUPROSTENOL SODIUM ()
[3H](+)-fluprostenol ()
Fluoprostenol ()
ICI-81008 ()
ICI 80,008 [AS SODIUM SALT] ()
Fluprostenol sodium salt ()
Sodium fluprostenol ()
ICI-80008 ()
ICI 80,008 ()
Equimate ()
ICI 81,008 ()
Fluprostenol-d4 ()
P&D ID
PD014179
CAS
40666-16-8
54276-17-4
Tags
drug candidate
natural product
drug
available
Drug Status
approved
vet_approved
Approved by
FDA
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION The INN-assigned compound fluprostenol is a racemic mixture of two enantiomers. The structure shown here shows the stereochemistry of the more active of these enantiomers, and the PubChem and ChEMBL entries linked to in the table above also represent this enantiomer. For an alternative stereoisomers see CID 6436637. (GtoPdb)
Compound Sets
13
Cayman Chemical Bioactives
316767
16768
ChEMBL Drugs
CHEMBL1201379
CHEMBL2107435
Concise Guide to Pharmacology 2017/18
1940
3417
Concise Guide to Pharmacology 2019/20
1940
3417
Concise Guide to Pharmacology 2021/22
1940
3417
Concise Guide to Pharmacology 2023/24
1940
3417
DrugBank
DB11519
DrugBank Approved Drugs
DB11519
DrugCentral
5546
DrugMAP
DM9Q2PG
Guide to Pharmacology
1940
3417
MedChem Express Bioactive Compound Library
HY-108560
NPC Screening Collection
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
458.19
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
4
Rotatable Bonds
11
Ring Count
2
Aromatic Ring Count
1
cLogP
3.56
TPSA
107.22
Fraction CSP3
0.52
Chiral centers
5.0
Largest ring
6.0
QED
0.3
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Target
Prostaglandin Receptor
Source data