General
Preferred name
EPRAZINONE
Synonyms
Eprazinona ()
Eprazinone 2HCl ()
NSC 317935 ()
Resplen ()
Eftapan ()
Mucitux ()
Eprazinone dihydrochloride ()
Eprazinone (dihydrochloride) ()
Eprazinone hydrochloride ()
Eprazinone (hydrochloride) ()
P&D ID
PD014150
CAS
10402-53-6
10402-90-1
Tags
natural product
drug
available
Drug Status
experimental
approved
withdrawn
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Eprazinone dihydrochloride is a drug with proposed mucolytic, secretolytic, and bronchial antispasmodic properties. Eprazinone dihydrochloride is a neurokinin 1 receptor (NK1R) ligand. It has the potential for chronic bronchitis treatment that improved pulmonary function and arterial partial pressure of oxygen.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
DrugCentral
DrugCentral Approved Drugs
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
41
Molecular Weight
380.25
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
9
Ring Count
3
Aromatic Ring Count
2
cLogP
3.9
TPSA
32.78
Fraction CSP3
0.46
Chiral centers
2.0
Largest ring
6.0
QED
0.62
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
R05CB04
Toxicity type
NULL
Pathway
GPCR/G protein
Neuronal Signaling
Target
Neurokinin Receptor
Solubility
Soluble in Methanol (Slightly), Water (Slightly)
Source data
