General
Preferred name
Trimethyltetradecylammonium
Synonyms
Tetradonium bromide ()
CETRIMIDE ()
MitMAB ()
tetradecyl trimethyl ammonium bromide ()
Tetradecyltrimethylammonium bromide ()
Tetradecyltrimethylammonium (bromide) ()
P&D ID
PD014148
CAS
1119-97-7
10182-92-0
8044-71-1
2253617-91-1
Tags
available
drug candidate
nuisance
Drug Status
investigational
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Inhibitor of LFA-1/ICAM mediated cell adhesion
(Tocris Bioactive Compound Library)
DESCRIPTION
MitMAB, an organic building block and cationic surfactant, is a dynamin inhibitor that inhibits the GTPase activity of dynamin I (Ki = 940 nM; IC50 = 3.1 μM). It has been used in a study to assess a surfactant-controlled synthetic method to obtain a nanophase of mesoporous ceria-zirconia solid solution containing cationic defects in the crystalline structure.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
DrugBank
NPC Screening Collection
Nuisance compounds in cellular assays
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
44
Molecular Weight
256.3
Hydrogen Bond Acceptors
0
Hydrogen Bond Donors
0
Rotatable Bonds
13
Ring Count
0
Aromatic Ring Count
0
cLogP
5.39
TPSA
0.0
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
0.0
QED
0.31
Structural alerts
1
Surfactant
Nuisance compounds
Related compounds
Custom attributes
(extracted from source data)
Target
Dnm1 GTPase
Primary Target
Dynamin
MOA
Inhibitor
Pathway
Cytoskeletal Signaling
Solubility
Freely soluble in Chloroform, Ethanol (95%), Water
Practically insoluble in Ether
Source data
