General
Preferred name
TRIDOLGOSIR
Synonyms
Swainsonine, (2 beta,8a alpha)-isomer ()
Swainsonine ()
TRIDOLGOSIR HYDROCHLORIDE ()
GD0039 ()
GD-0039 ()
P&D ID
PD014053
CAS
72741-87-8
214462-68-7
Tags
available
drug candidate
natural product
Drug indication
Solid tumour/cancer
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugMAP
Mcule NIBR MoA Box Subset
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
38
Properties
(calculated by RDKit )
Molecular Weight
173.11
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
0
Ring Count
2
Aromatic Ring Count
0
cLogP
-1.45
TPSA
63.93
Fraction CSP3
1.0
Chiral centers
4.0
Largest ring
6.0
QED
0.42
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
member
MOA
alpha-Mannosidase Inhibitors
alpha mannosidase inhibitor
Target
MAN2A1
antibiotic
Pathway
Anti-infection
Apoptosis
Source data
