General
Preferred name
BUTAPROST
Synonyms
(R)-Butaprost ()
BAY-Q-4218 ()
BAYQ-4218 ()
TR-4979 ()
BAY Q 4218 ()
P&D ID
PD013976
CAS
69648-38-0
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
The structure of butaprost shown on this ligand entry is the same as that of the INN-assigned structure. A second form of the ligand, is often used experimentally and is also listed on our website. Representations of butaprost on other databases and in the literature may show the free acid form.
(GtoPdb)
DESCRIPTION
Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugMAP
Guide to Pharmacology
NPC Screening Collection
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
19
Molecular Weight
408.29
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
13
Ring Count
2
Aromatic Ring Count
0
cLogP
4.34
TPSA
83.83
Fraction CSP3
0.83
Chiral centers
4.0
Largest ring
5.0
QED
0.27
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
prostaglandin receptor agonist
Source data
