General
Preferred name
DOPEXAMINE
Synonyms
FPL-60278AR ()
Dopacard ()
Dopexamine HCl ()
FPL60278AR ()
DOPEXAMINE HYDROCHLORIDE ()
FPL 60278 ()
FPL-60278 ()
FPL 60278AR ()
Dopexamine dihydrochloride ()
P&D ID
PD013931
CAS
86484-91-5
86197-47-9
Tags
available
drug
First approval
1989
Drug Status
investigational
approved
Drug indication
Cardiac failure
Cardiovascular Agent
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Other bioactive compounds
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
47
Properties
(calculated by RDKit )
Molecular Weight
356.25
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
4
Rotatable Bonds
13
Ring Count
2
Aromatic Ring Count
2
cLogP
3.62
TPSA
64.52
Fraction CSP3
0.45
Chiral centers
0.0
Largest ring
6.0
QED
0.33
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Target
??2-adrenergic receptor
Adrenergic Receptor
Member status
member
MOA
Dopamine D1 Agonists
beta2-Adrenoceptor Agonists
Source data
