General
Preferred name
flupentixol
Synonyms
flupenthixol ()
Flupenthixol, Beta ()
FLUPENTHIXOL, Alpha ()
Flupenthixol dihydrochloride ()
Emergil ()
P&D ID
PD013866
CAS
2413-38-9
2709-56-0
Tags
natural product
drug
available
First approval
1964
Drug Status
approved
withdrawn
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Selective 5-HT2B antagonist
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
Ki Database
NPC Screening Collection
Tocris Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
26
Molecular Weight
434.16
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
2
cLogP
4.6
TPSA
26.71
Fraction CSP3
0.39
Chiral centers
0.0
Largest ring
6.0
QED
0.63
Structural alerts
1
styrene_B(8)
c:1:c:c-2:c(:c:c:1)-[#6](-c:3:c(-[$([#16;X2]),$([#6;X4])]-2):c:c:[c;!H0,$(c-[#17]),$(c-[#6;X4])](:c:3))=[#6]-[#6]
PAINS Family C
Related compounds
Custom attributes
(extracted from source data)
Primary Target
Non-selective Dopamine
Pathway
GPCR/G protein
Target
dopamine
MOA
Antagonist
ATC
N05AF01
Source data
