General
Preferred name
carindacillin
Synonyms
CARBENICILLIN INDANYL SODIUM ()
Carindacillin (sodium) ()
CP-15464-2 ()
CARBENICILLIN INDANYL ()
Carindacilline ()
Carindacillin ()
Indanyl carbenicillin ()
Carindacilina ()
CP-15,464-2 ()
Carindacillin sodium salt ()
Carindacillin Sodium ()
Geocillin ()
P&D ID
PD013746
CAS
35531-88-5
26605-69-6
Tags
available
prodrug
drug
Approved by
FDA
First approval
1972
Drug indication
osteomyelitis
Bacterial infection
Drug Status
approved
investigational
withdrawn
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Carindacillin is a semisynthetic carboxypenicillin belonging to the β-lactam class of antibacterial compounds. It is an orally bioavailable prodrug that is hydrolysed into . (GtoPdb)
DESCRIPTION Carindacillin (Carbenicillin indanyl) sodium is an orally active and broad-spectrum antimicrobial agent. Carindacillin sodium can be hydrolyzed to Carbenicillin in vivo. Carindacillin sodium can be used for the research of urinary-tract infection[1][2].
Compound Sets
11
ChEMBL Approved Drugs
CHEMBL1596
CHEMBL1200991
ChEMBL Drugs
CHEMBL1596
CHEMBL1200991
DrugBank
DB09319
DrugBank Approved Drugs
DB09319
DrugCentral
508
DrugCentral Approved Drugs
508
DrugMAP
DME2XG3
DrugMAP Approved Drugs
DME2XG3
Guide to Pharmacology
12276
MedChem Express Bioactive Compound Library
HY-108880
NPC Screening Collection
External IDs
43
Properties
(calculated by RDKit )
Molecular Weight
494.15
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
6
Ring Count
5
Aromatic Ring Count
2
cLogP
2.5
TPSA
113.01
Fraction CSP3
0.38
Chiral centers
4.0
Largest ring
6.0
QED
0.27
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Therapeutic Class
Antiinfective Agents
Pathway
Anti-infection
Target
Bacterial
Source data