General
Preferred name
ADEFOVIR
Synonyms
GS-0393 ()
PMEA ()
GS 0393 ()
Adefovir-d4 ()
P&D ID
PD013718
CAS
106941-25-7
1190021-70-5
Tags
available
drug
prodrug
Drug indication
Herpes simplex virus infection
Antiviral
Hepatitis B virus infection
Discovery agent
Drug Status
approved
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
8
Organisms
12
Compound Sets
13
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugMAP Approved Drugs
DrugMatrix
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NPC Screening Collection
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
40
Properties
(calculated by RDKit )
Molecular Weight
273.06
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
3
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
2
cLogP
-0.44
TPSA
136.38
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.49
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
hepatitis B
MOA
DNA polymerase inhibitor
Pathway
Anti-infection
Target
HBV
Reverse Transcriptase
Source data
