General
Preferred name
DITHIAZANINE
Synonyms
Dithiazanine iodide ()
Delvex ()
Telmide ()
Vercidon ()
Abminthic ()
Netocyd ()
NSC 221154 ()
3-ethyl-2-[(1E,3E)-5-[(2E)-3-ethyl-2,3-dihydro-1,3-benzothiazol-2-ylidene]penta-1,3-dien-1-yl]-1,3-benzothiazol-3-ium ()
Dithiazanine cation ()
Dithiazanine ion ()
Dithiazanine ()
Ioduro de ditiazanina ()
Iodure de dithiazanine ()
NSC-221154 ()
P&D ID
PD013703
CAS
7187-55-5
1186-69-2
514-73-8
Tags
available
drug
Approved by
FDA
Drug Status
vet_approved
approved
withdrawn
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
PUBCHEM_BIOASSAY: High Throughput Imaging Assay for Beta-Casein. High Throughput Imaging Assay for Beta-Casein. The assay involves exposing HeLa cells to test compounds which are then immunostained and imaged for endogenous beta-casein. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1685]; PUBCHEM_BIOASSAY: XBP1 DR counterscreen for CHOP. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2732 AID493217]
(TargetMol Bioactive Compound Library)
DESCRIPTION
Dithiazanine iodide (Netocyd) is a benzothiazole. It has been used as an antinematodal agent. It also has been effective as a nanoparticle in treating glioblastoma.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
1
Compound Sets
11
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
LSP-MoA library (Laboratory of Systems Pharmacology)
NPC Screening Collection
ReFrame library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
58
Molecular Weight
391.13
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
3
cLogP
6.25
TPSA
7.12
Fraction CSP3
0.17
Chiral centers
0.0
Largest ring
6.0
QED
0.37
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
A
Toxicity type
cardiovascular
Source data
