General
Preferred name
OXATOMIDE
Synonyms
Oxatimide ()
Tinset ()
R 35,443 ()
Cobiona ()
Celtect ()
R-35443 ()
Dasten ()
NSC-309710 ()
P&D ID
PD013659
CAS
60607-34-3
Tags
available
drug
First approval
1981
Drug Status
investigational
approved
Drug indication
Anti-Allergic
Hay fever
Anti-Asthmatic
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
2
Compound Sets
13
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
33
Properties
(calculated by RDKit )
Molecular Weight
426.24
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
5
Aromatic Ring Count
4
cLogP
4.13
TPSA
44.27
Fraction CSP3
0.3
Chiral centers
0.0
Largest ring
6.0
QED
0.48
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
allergic rhinitis
Target
HRH1
5-HT Receptor
Histamine Receptor
P2X Receptor
MOA
Histamine Receptor antagonist
Therapeutic Class
Antiallergic Agents
Pathway
GPCR/G protein
Immunology/Inflammation
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data
