General
Preferred name
LINOLEIC ACID
Synonyms
9,12-octadecadienoic acid ()
acidelinoleique ()
9,12-Linoleic acid ()
Linoleate (sodium) ()
DEULINOLEIC ACID ()
Linoleic Acid-d4 ()
Linoleic Acid-d11 ()
Linoleic Acid (sodium salt) ()
Linoleate ()
Linolic acid ()
C18:2 (n-6) ()
Ronacare asc 3 ()
Unifac 6550 ()
Linoleic acid component of vitamin f ()
NSC-281243 ()
9,12-linoleic acid ()
FEMA NO. 3380, LINOLEIC ACID- ()
Polylin 515 ()
Emersol 315 ()
SODIUM LINOLATE ()
11,11-dideuterolinoleic acid ()
Acido deulinoleico ()
11,11-d2-linoleic acid ()
Acide deulinoleique ()
Linoleic Acid-13C18 ()
P&D ID
PD013641
CAS
60-33-3
506-21-8
2197-37-7
80969-37-5
822-17-3
79050-23-0
287111-25-5
Tags
available
drug candidate
drug
Drug indication
Discovery agent
Neoplasm
Drug Status
approved
experimental
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Linoleic acid is an essential ω-6 polyunsaturated fatty acid. It is the most abundant PUFA in a variety of foods, and dietary sources of linoleic acid include vegetable oils, meats, nuts, seeds, and eggs. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism. (Enamine Bioactive Compounds)
DESCRIPTION Linoleic acid (9,12-octadecadienoic acid) is a naturally occurring polyunsaturated fatty acid found in animal and vegetable oils. Linoleic acid is an essential fatty acid that is part of membrane phospholipids. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
1
Compound Sets
21
Cayman Chemical Bioactives
90150
9002193
390150
21909
31159
ChEMBL Drugs
CHEMBL267476
CHEMBL5095085
Concise Guide to Pharmacology 2017/18
1052
Concise Guide to Pharmacology 2019/20
1052
Concise Guide to Pharmacology 2021/22
1052
Concise Guide to Pharmacology 2023/24
1052
Drug Repurposing Hub
DrugBank
DB14104
DrugBank Approved Drugs
DB14104
DrugCentral
3323
DrugCentral Approved Drugs
3323
DrugMAP
DMDGPY9
Enamine Bioactive Compounds
EBC-26431
Guide to Pharmacology
1052
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL267476
MedChem Express Bioactive Compound Library
HY-N0729
HY-W011398
NPC Screening Collection
NURSA ligand set
nursa/index.jsf?doi=10.1621%2F78C92792E0
ReFrame library
Selleckchem Bioactive Compound Library
linoleic-acid
TargetMol Bioactive Compound Library
T4P2931
External IDs
94
Properties
(calculated by RDKit )
Molecular Weight
280.24
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
14
Ring Count
0
Aromatic Ring Count
0
cLogP
5.88
TPSA
37.3
Fraction CSP3
0.72
Chiral centers
0.0
Largest ring
0.0
QED
0.32
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
FABP4, FFAR1, FFAR4, HNF4A, KCNB1, PPARG, TRPM8
Interleukin Related
JNK
NF-κB
MOA
Oxidative stress inducer
Pathway
Metabolism
Immunology/Inflammation
MAPK/ERK Pathway
Metabolic Enzyme/Protease
Source data