General
Preferred name
BETAMETHASONE DIPROPIONATE
Synonyms
Diprolene ()
Diprolene AF ()
Diprosone ()
BETAMETHASONE 17,21-DIPROPIONATE ()
SCH 11460 ()
Alphatrex ()
Betamethasone dipropionate component of leo-90100 ()
Betamethasone dipropionate component of lotrisone ()
Betamethasone 17,21-dipropionate ()
Sernivo ()
Betamethasone (as dipropionate) ()
Betamethasone dipropionate component of taclonex ()
NSC-758415 ()
Maxivate ()
SCH-11460 ()
Betamethasone dipropionate component of enstilar ()
Betamethasone dipropionate component of wynzora ()
Diprospan ()
Rinderon dp ()
P&D ID
PD013632
CAS
5593-20-4
Tags
available
drug
Approved by
FDA
First approval
1975
Drug Status
vet_approved
approved
Max Phase
4.0
Drug indication
psoriasis
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.
PRICE 29
DESCRIPTION Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate (SCH 11460) binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. (TargetMol Bioactive Compound Library)
Compound Sets
12
AdooQ Bioactive Compound Library
A10130
Cayman Chemical Bioactives
39499
ChEMBL Approved Drugs
CHEMBL1200384
ChEMBL Drugs
CHEMBL1200384
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugCentral
353
DrugCentral Approved Drugs
353
MedChem Express Bioactive Compound Library
HY-13571
NPC Screening Collection
Selleckchem Bioactive Compound Library
Betamethasone-Dipropionate(Diprolene)
TargetMol Bioactive Compound Library
T1559
External IDs
35
Properties
(calculated by RDKit )
Molecular Weight
504.25
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
1
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
0
cLogP
3.82
TPSA
106.97
Fraction CSP3
0.71
Chiral centers
8.0
Largest ring
6.0
QED
0.55
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Glucocorticoid Receptor
NR3C1
Indication
corticosteroid-responsive dermatoses
MOA
anti-inflammatory agent
Pathway
Immunology/Inflammation
Vitamin D Related/Nuclear Receptor
Endocrinology/Hormones
Source data