General
Preferred name
OXYFEDRINE
Synonyms
Modacor ()
Oxyfedrine L-form hydrochloride ()
D563 ()
Ildamen ()
D 563 ()
D-563 ()
Oxyfedrine (hydrochloride) ()
Oxyfedrine L-form HCl ()
(-)-oxyfedrine ()
Oxifedrina ()
P&D ID
PD013630
CAS
16777-42-7
10084-20-5
21071-51-2
15687-41-9
Tags
available
drug
Drug Status
approved
experimental
investigational
Max Phase
2.0
Drug indication
Cardiovascular disease
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Oxyfedrine hydrochloride, a vasodilator, is an orally active ¦Â-adrenoreceptor agonist. Oxyfedrine decreases the tonicity of coronary vessels. Oxyfedrine hydrochloride can be used in the research of cardiovascular disease[1][2].
PRICE 257
DESCRIPTION Oxyfedrine L-form HCl (Ildamen) is a partial agonist at beta-adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent. (TargetMol Bioactive Compound Library)
Compound Sets
8
ChEMBL Drugs
CHEMBL1651913
Drug Repurposing Hub
DrugBank
DB13398
DrugCentral
2030
DrugCentral Approved Drugs
2030
MedChem Express Bioactive Compound Library
HY-108300
NPC Screening Collection
TargetMol Bioactive Compound Library
T24579
External IDs
34
Properties
(calculated by RDKit )
Molecular Weight
313.17
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
8
Ring Count
2
Aromatic Ring Count
2
cLogP
2.98
TPSA
58.56
Fraction CSP3
0.32
Chiral centers
2.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
β-adrenergic receptor
Adrenergic Receptor
Indication
angina pectoris
MOA
Adrenergic Receptor agonist
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Source data