General
Preferred name
CARBOPROST
Synonyms
15(S)-15-Methyl Prostaglandin F2α ()
15-Methyl-PGF2α ()
CARBOPROST TROMETHAMINE ()
Carboprost (tromethamine) ()
15(S)-15-Methyl Prostaglandin F2¦Á ()
15-Methyl-PGF2¦Á ()
15(S)-15-methyl Prostaglandin F2.alpha. ()
15-methyl-pgf2.alpha. ()
(15s)-15-methyl-pgf2.alpha. ()
U-32,921 ()
15-methylprostaglandin f2.alpha. ()
Hemabate ()
U-32921 ()
Carboprost tromethamine salt ()
Carboprost trometamol ()
U-32,921E ()
Carboprost Trometanol ()
Prostin/15m ()
U-32921E ()
P&D ID
PD013601
CAS
58551-69-2
59286-19-0
35700-23-3
Tags
available
drug
Approved by
FDA
First approval
1979
Drug indication
postpartum hemorrhage
Abortion
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Carboprost (15(S)-15-Methyl Prostaglandin F2¦Á) is a metabolically stable synthetic analog of prostaglandin F2¦Á. Carboprost stimulates uterine contractions and induces abortion. Carboprost is used for postpartum hemorrhage due to uterine atony and for the termination of pregnancy in the second trimester[1][2].
PRICE 146
DESCRIPTION Carboprost (15(S)-15-Methyl Prostaglandin F2??) is a synthetic analogue of PGF2?? with oxytocic properties, commonly used to restore uterine tone.
DESCRIPTION Carboprost tromethamine is the synthetic 15-methyl analogue of prostaglandin F2¦Á. Carboprost tromethamine can effectively promote law contraction of the uterus and significantly reduce the amount of bleeding during and after delivery[1][2].
DESCRIPTION Carboprost is a synthetic prostaglandin analogue of PGF2α with oxytocic properties. It is a potent uterine stimulant and abortifacient which can be given intramuscularly to induce labor. It can also induce luteolysis and reduces serum progesterone concentrations. (BOC Sciences Bioactive Compounds)
DESCRIPTION Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic analogue of PGF2α with oxytocic properties, commonly used to restore uterine tone. (TargetMol Bioactive Compound Library)
DESCRIPTION Adrenergic alpha receptor antagonist; antihypertensive (Tocris Bioactive Compound Library)
Compound Sets
16
BOC Sciences Bioactive Compounds
carboprost-cas-35700-23-3-item-66990
Cayman Chemical Bioactives
16743
ChEMBL Approved Drugs
CHEMBL1237122
CHEMBL1237105
ChEMBL Drugs
CHEMBL1237122
CHEMBL1237105
DrugBank
DB19356
DB00429
DrugBank Approved Drugs
DB19356
DB00429
DrugCentral
502
DrugCentral Approved Drugs
502
DrugMAP
DMS3508
DrugMAP Approved Drugs
DMS3508
MedChem Express Bioactive Compound Library
HY-128428
HY-A0195
NCATS Inxight Approved Drugs
7B5032XT6O
NPC Screening Collection
Selleckchem Bioactive Compound Library
carboprost
TargetMol Bioactive Compound Library
T22285
Tocris Bioactive Compound Library
6428
External IDs
49
Properties
(calculated by RDKit )
Molecular Weight
368.26
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
4
Rotatable Bonds
12
Ring Count
1
Aromatic Ring Count
0
cLogP
3.43
TPSA
97.99
Fraction CSP3
0.76
Chiral centers
5.0
Largest ring
5.0
QED
0.31
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
prostaglandin F2α
Prostaglandin Receptor
Primary Target
Prostanoid Receptors
MOA
Agonist
Pathway
GPCR/G protein
Immunology/Inflammation
Therapeutic Class
Abortifacient Agents
Source data