General
Preferred name
Propagermanium
Synonyms
Dipropanoic acid germanium sequioxide ()
SK-818 ()
Ge 132 ()
Ge132 ()
SK 818 ()
Ge-132 ()
proxigermanium ()
P&D ID
PD013579
CAS
12758-40-6
122402-75-9
126595-07-1
Tags
available
contains metal
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 58
DESCRIPTION Propagermanium is an organometallic compound of germanium that is sold as an alternative medicine for the treatment of Hepatitis B under the development of Astellas Pharma and Sanwa Kagaku Kenkyusho. (BOC Sciences Bioactive Compounds)
DESCRIPTION Propagermanium (Ge132), an organometallic compound of germanium, has been used as a therapeutic agent against chronic hepatitis B in Japan. (TargetMol Bioactive Compound Library)
Compound Sets
5
BOC Sciences Bioactive Compounds
propagermanium-cas-126595-07-1-item-475253
Drug Repurposing Hub
NPC Screening Collection
ReFrame library
TargetMol Bioactive Compound Library
T20641
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
341.89
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
8
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.21
TPSA
117.97
Fraction CSP3
0.67
Chiral centers
0.0
Largest ring
0.0
QED
0.59
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Indication
hepatitis B
Target
CCR2
MOA
CCR agonist, interferon receptor agonist
Solubility
Soluble in DMSO
Source data