General
Preferred name
OXANTEL
Synonyms
OXANTEL PAMOATE ()
Oxantel embonate ()
Oxantel (pamoate) ()
P&D ID
PD013523
CAS
42408-84-4
68813-55-8
36531-26-7
Tags
available
drug
Drug indication
Trichuris trichiura infection
Helminthiasis
Drug Status
approved
experimental
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Oxantel pamoate (Oxantel embonate) is an anthelmintic agent that potently against Trichuris muris. Oxantel pamoate inhibits fumarate reductase (Frd) activity in some pathogenic bacteria and inhibits P. gingivalis homotypic biofilm formation (IC50 of 2.2 ¦ÌM)[1][2].
DESCRIPTION
Oxantel is an anthelmintic agent. In addition, it inhibits fumarate reductase, an enzyme that is crucial for the survival of pathogenic bacteria in the biofilm in periodontal pockets. It has been suggested that oxantel might guard against chronic periodontitis, but efficacy of this potential antibacterial function is yet to be confirmed .
(GtoPdb)
DESCRIPTION
Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
16
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
35
Molecular Weight
216.13
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
2.14
TPSA
35.83
Fraction CSP3
0.31
Chiral centers
0.0
Largest ring
6.0
QED
0.82
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Antiparasitic
Parasite
Indication
gastrointestinal parasites
MOA
anthelmintic agent
Pathway
Microbiology/virology
Anti-infection
Therapeutic Class
Anthelmintics
Source data
