General
Preferred name
FLUROFAMIDE
Synonyms
Eu-4534 ()
NSC-342995 ()
Flurfamide ()
EU-4534 ()
Flurofamida ()
P&D ID
PD013446
CAS
70788-28-2
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Flurofamide is a potent bacterial urease inhibitor with potential in the treatment of infection induced urinary stones[1].
PRICE 40
DESCRIPTION urease inhibitor (Tocriscreen Plus)
DESCRIPTION urease inhibitor (Tocriscreen Total)
DESCRIPTION COMT inhibitor (Tocris Bioactive Compound Library)
DESCRIPTION Flurofamide is a bacterial urease inhibitor used for the treatment of gastritis and irregular urease activity in the urinary tract. (BOC Sciences Bioactive Compounds)
DESCRIPTION Flurofamide is an effective bacterial urease inhibitor and has potential in the treatment of infected urinary calculi. (TargetMol Bioactive Compound Library)
Compound Sets
11
BOC Sciences Bioactive Compounds
flurofamide-cas-70788-28-2-item-41933
ChEMBL Drugs
CHEMBL144620
Drug Repurposing Hub
DrugMatrix
MedChem Express Bioactive Compound Library
HY-100956
NPC Screening Collection
ReFrame library
TargetMol Bioactive Compound Library
T11305
Tocris Bioactive Compound Library
0478
Tocriscreen Plus
0478
Tocriscreen Total
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
217.04
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
0.58
TPSA
98.21
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.63
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Enzymes
Primary Target
Other Hydrolases
MOA
Inhibitor
urease inhibitor
Pathway
Anti-infection
Target
Bacterial
Source data