General
Preferred name
HESPERIDIN
Synonyms
Hesperetin-7-rutinoside ()
Hesperetin 7-rutinoside ()
Cirantin ()
Hesperidin ()
HESPERIDINE ()
Diosvein ()
NSC-31048 ()
P&D ID
PD013341
CAS
106904-63-6
520-26-3
Tags
available
drug
Drug indication
Osteoporosis
Vascular purpura
Drug Status
approved
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities[1][2].
PRICE
41
DESCRIPTION
Hesperidin (Cirantin) is a flavanone glycoside found in citrus fruits with antioxidant, anti-inflammatory, anti-carcinogenic, and antihypertensive and lipid-lowering activity.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
41
Molecular Weight
610.19
Hydrogen Bond Acceptors
15
Hydrogen Bond Donors
8
Rotatable Bonds
7
Ring Count
5
Aromatic Ring Count
2
cLogP
-1.16
TPSA
234.29
Fraction CSP3
0.54
Chiral centers
11.0
Largest ring
6.0
QED
0.18
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
NF-¦ÊB
Apoptosis
Immunology/Inflammation
Metabolism
NF-κB
Metabolic Enzyme/Protease
MOA
Autophagy
flavanone glycoside
Target
AURKB, CACNA1B
Endogenous Metabolite
Reactive Oxygen Species (ROS)
Reactive Oxygen Species
Source data
