General
Preferred name
NAPROXEN
Synonyms
Naproxen sodium,(-) ()
(±)-Naproxen ()
(Rac)-Naproxen ()
2-(6-Methoxynaphthalen-2-yl)propanoic acid ()
(¡À)-Naproxen ()
(±)-Naproxen-d3 ()
(+/-)-Naproxen ()
P&D ID
PD013333
CAS
23981-80-8
26159-31-9
958293-77-1
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
(¡À)-Naproxen ((Rac)-Naproxen) is a racemate of Naproxen (HY-15030). Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 ¦ÌM, respectively.
DESCRIPTION
(+/-)-Naproxen is a COX-1 and COX-2 inhibitor.
(Enamine Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
Cayman Chemical Bioactives
DrugMatrix
Enamine Bioactive Compounds
Ki Database
MedChem Express Bioactive Compound Library
Other bioactive compounds
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
43
Molecular Weight
230.09
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
3.04
TPSA
46.53
Fraction CSP3
0.21
Chiral centers
1.0
Largest ring
6.0
QED
0.88
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
COX
Pathway
Immunology/Inflammation
Source data
