General
Preferred name
PRIDINOL
Synonyms
PRIDINOL METHANESULFONATE ()
Ridinol ()
Pridinol methanesulfonate salt ()
Pridinol (mesylate) ()
Loxeen ()
NSC-23016 ()
C-238 ()
Pridinol (hydrochloride) ()
P&D ID
PD013310
CAS
511-45-5
6856-31-1
968-58-1
Tags
available
drug
Drug Status
approved
experimental
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Pridinol mesylate is an orally active, blood-brain permeable, muscarinic acetylcholine receptor (mAChR)-directed muscle relaxant. Pridinol mesylate reduces the conduction of impulses to spinal motor neurons and exerts muscle relaxant activity. Pridinol mesylate inhibits skeletal muscle contractures in diseases of both central and peripheral origin and can be used in research in the field of musculoskeletal diseases[1][2].
DESCRIPTION Loxeen (Pridinol methanesulfonate) is used as an anticholinergic and as an antiparkinsonian agent. (TargetMol Bioactive Compound Library)
Compound Sets
13
Cayman Chemical Bioactives
36056
ChEMBL Drugs
CHEMBL404215
Drug Repurposing Hub
DrugBank
DB13642
DrugCentral
2263
DrugCentral Approved Drugs
2263
DrugMatrix
MedChem Express Bioactive Compound Library
HY-B1343
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
TargetMol Bioactive Compound Library
T1072
The Spectrum Collection
External IDs
55
Properties
(calculated by RDKit )
Molecular Weight
295.19
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
2
cLogP
3.8
TPSA
23.47
Fraction CSP3
0.4
Chiral centers
0.0
Largest ring
6.0
QED
0.91
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
mAChR
Cholinesterase (ChE)
Indication
muscle relaxant
Pathway
Neuroscience
Neuronal Signaling
Source data