General
Preferred name
DEXAMETHASONE ACETATE
Synonyms
BETAMETHASONE ACETATE ()
Hexadecadrol (acetate) ()
Dexamethasone 21-acetate ()
NSC 39471 ()
Dexamethason acetate ()
Hexadecadrol acetate ()
NSC 39471,Dexamethasone 21-acetate ()
NSC-39471 ()
Dexamethasone acetate monohydrate ()
Dectancyl ()
Decadron-La ()
Dexamethasoni acetas ()
Fortecortin (crystal suspension) ()
Decadron ()
Dexamethasoni acetas monohydrate ()
Dexamethasone acetate anhydrous ()
P&D ID
PD013304
CAS
1177-87-3
Tags
prodrug
natural product
drug
available
Approved by
FDA
First approval
1973
Drug Status
investigational
withdrawn
approved
vet_approved
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Compound Sets
14
Cayman Chemical Bioactives
22286
ChEMBL Approved Drugs
CHEMBL1530428
ChEMBL Drugs
CHEMBL1530428
Drug Repurposing Hub
DrugBank
DB14649
DrugBank Approved Drugs
DB14649
DrugCentral
826
DrugCentral Approved Drugs
826
MedChem Express Bioactive Compound Library
HY-14648A
NPC Screening Collection
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
dexamethasone-acetate
TargetMol Bioactive Compound Library
T0947
Withdrawn 2.0
245
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
434.21
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
0
cLogP
2.47
TPSA
100.9
Fraction CSP3
0.71
Chiral centers
8.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Immunology/Inflammation
Metabolism
Anti-infection
Autophagy
Vitamin D Related/Nuclear Receptor
Target
Annexin A1
Glucocorticoid Receptor
IL Receptor
Inos
antibiotic
Bacterial
Complement System
Mitophagy
SARS-CoV
Complement System,COVID-19,IL Receptor
Disease Area
endocrinology, rheumatology, allergy, gastroenterology, hematology, neurology/psychiatry, dermatology
Indication
hypercalcemia, rheumatoid arthritis, psoriatic arthritis, osteoarthritis, allergic rhinitis, ulcerative colitis, anemia, multiple sclerosis, enteritis, lupus, dermatitis herpetiformis (DH), nephrotic syndrome, psoriasis
MOA
Glucocorticoid Receptor agonist
ATC
A01AC02
C05AA09
D07AB19
D07XB05
D10AA03
H02AB02
R01AD03
S01BA01
S01CB01
S02BA06
S03BA01
Source data