General
Preferred name
desoxycortone
Synonyms
deoxycorticosterone ()
DESOXYCORTICOSTERONE ()
Desoxycorticosteronum ()
11-deoxy Corticosterone ()
P&D ID
PD013278
CAS
64-85-7
Tags
available
drug
Drug indication
Discovery agent
Drug Status
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. Deoxycorticosterone is an agonist for O. mykiss mineralocorticoid receptor (rtMR) transcription with EC50 of 0.16 nM[3]. Deoxycorticosterone could acts as an immune stimulator in fish[4].
PRICE
47
DESCRIPTION
Administered as desoxycortone pivalate (Zycortal®) as a veterinary medicine to replace the missing in dogs with Addison's disease.
(GtoPdb)
DESCRIPTION
Deoxycorticosterone (Desoxycortone) is a steroid metabolite produced by the adrenal gland. Deoxycorticosterone is an aldosterone precursor and possesses mineralocorticoid activity.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugCentral
DrugCentral Approved Drugs
DrugMAP
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
NURSA ligand set
Prestwick Chemical Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
55
Molecular Weight
330.22
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
3.7
TPSA
54.37
Fraction CSP3
0.81
Chiral centers
6.0
Largest ring
6.0
QED
0.84
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Human Endogenous Metabolite
NR3C1, NR3C2
Endogenous Metabolite
Mineralocorticoid Receptor
MOA
mineralocorticoid receptor agonist
Pathway
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Metabolism
Source data
