General
Preferred name
eticlopride
Synonyms
Eticlopride hydrochloride ()
S(-)Eticlopride hydrochloride ()
Eticlopride (hydrochloride) ()
P&D ID
PD013273
CAS
97612-24-3
84226-12-0
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Potent and selective non-peptide AT1 antagonist
(Tocris Bioactive Compound Library)
DESCRIPTION
Selective D2/D3 antagonist
(Tocriscreen Total)
DESCRIPTION
Eticlopride hydrochloride is a selective dopamine D2/D3 receptor antagonist (Ki = 0.50 and 0.16 nM, respectively).
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Eticlopride is a selective dopamine D2 antagonist . It was initially developed as a potential antipsychotic agent. Now Eticlopride is primarily used in pharmacological research.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
3
Compound Sets
12
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
Prestwick Chemical Library
Tocris Bioactive Compound Library
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
35
Molecular Weight
340.16
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
6
Ring Count
2
Aromatic Ring Count
1
cLogP
2.83
TPSA
61.8
Fraction CSP3
0.59
Chiral centers
1.0
Largest ring
6.0
QED
0.84
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
Non-selective Dopamine
MOA
Antagonist
Dopamine Receptor antagonist
Target
DRD2, DRD3, DRD4
Dopamine Receptor
Pathway
GPCR/G protein
Neuronal Signaling
Solubility
Soluble in DMSO
Source data
