General
Preferred name
FIPEXIDE
Synonyms
FIPEXIDE HYDROCHLORIDE ()
Fipexide (hydrochloride) ()
Fipexida ()
NSC-758407 ()
P&D ID
PD013233
CAS
34161-24-5
34161-23-4
Tags
available
drug
Drug Status
approved
experimental
withdrawn
Max Phase
4.0
Drug indication
Attention deficit hyperactivity disorder
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Fipexide hydrochloride, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide hydrochloride reduces striatal adenylate cyclase activity. Fipexide hydrochloride has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide hydrochloride is used for senile dementia research. Fipexide hydrochloride acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection[1][2].
PRICE 29
DESCRIPTION Fipexide, a parachloro-phenossiacetic acid derivative, is an orally active nootropic agent. Fipexide reduces striatal adenylate cyclase activity. Fipexide has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide is used for senile dementia research. Fipexide acts as a chemical inducer in callus formation, shoot regeneration and Agrobacterium infection[1][2].
DESCRIPTION Fipexide, a parachloro-phenossiacetic acid derivative, is a nootropic drug. Fipexide reduces striatal adenylate cyclase activity. Fipexide has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide is used for senile dementia research. (Enamine Bioactive Compounds)
DESCRIPTION Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983. It was served as a nootropic drug in France and Italy, mainly for the therapy of senile dementia, but is no longer in common use because of the occurrence of rare drug side-effects including hepatitis and fever. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
16
ChEMBL Approved Drugs
CHEMBL254857
ChEMBL Drugs
CHEMBL254857
Drug Repurposing Hub
DrugBank
DB13790
DrugCentral
1172
DrugCentral Approved Drugs
1172
Enamine Bioactive Compounds
EBC-08941
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
HY-B1124A
HY-B1124
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
fipexide-hydrochloride
TargetMol Bioactive Compound Library
T0322
The Spectrum Collection
Withdrawn 2.0
w13
External IDs
40
Properties
(calculated by RDKit )
Molecular Weight
388.12
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
2
cLogP
2.79
TPSA
51.24
Fraction CSP3
0.35
Chiral centers
0.0
Largest ring
6.0
QED
0.79
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Adenylate cyclase
dopamine
Dopamine Transporter
cAMP
MOA
psychoactive drug
ATC
N06BX05
Toxicity type
hepatic
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Source data