General
Preferred name
MECLOFENOXATE
Synonyms
MECLOFENOXATE HYDROCHLORIDE ()
Meclofenoxato ()
CENTROPHENOXINE HYDROCHLORIDE ()
Meclofenoxate (Centrophenoxine) HCl ()
Lucidril ()
Cerutil ()
Meclofenoxate HCl ()
Meclofenoxate HCl ()
Centrophenoxine ()
Meclofenoxate (hydrochloride) ()
Centrophenoxine (hydrochloride) ()
NSC-169411 ()
Cetrexin ()
Proseryl ()
ANP-235 ()
Meclofenoxane ()
Analux ()
P&D ID
PD013213
CAS
3685-84-5
51-68-3
1334-20-9
Tags
available
drug
Drug Status
approved
investigational
Max Phase
2.0
Drug indication
Attention deficit hyperactivity disorder
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Meclofenoxate (Centrophenoxine) hydrochloride is an ester synthesized from DMAE and pCPA, capable of crossing the blood-brain barrier, and can stimulate memory and enhance cognition[1][2][3].
DESCRIPTION
Nootropic; cholinergic drug
(LOPAC library)
DESCRIPTION
Meclofenoxate (Lucidril), also known as centrophenoxine, is a drug used to treat the symptoms of senile dementia and Alzheimer's disease. It is an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA). DMAE is a natural substance, found especially in fish. pCPA is a synthetic compound that resembles a variety of plant hormones called auxins.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Meclofenoxate hydrochloride (Lucidril) is an ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid. It has been shown to improve memory and general cognition, and mentally stimulating effect.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
18
AdooQ Bioactive Compound Library
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
Enamine Bioactive Compounds
Enamine BioReference Compounds
LOPAC library
MedChem Express Bioactive Compound Library
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
50
Molecular Weight
257.08
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
1
Aromatic Ring Count
1
cLogP
1.82
TPSA
38.77
Fraction CSP3
0.42
Chiral centers
0.0
Largest ring
6.0
QED
0.73
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Immunology/Inflammation
Membrane Transporter/Ion Channel
Metabolism
Neuroscience
Neuronal Signaling
Indication
senile dementia, Alzheimer's disease
MOA
nootropic agent
Target
Transferase
iGluR
nAChR
ALOX5
COX
Source data
