General
Preferred name
AMIPRILOSE
Synonyms
SM1213 ()
SM 1213 ()
SM-1213 ()
AMIPRILOSE HYDROCHLORIDE ()
SM -1213 (FREE BASE) ()
Therafectin ()
Amiprilose hcl ()
SM-1213 HYDROCHLORIDE ()
Amiprilosa ()
P&D ID
PD013212
CAS
60414-06-4
56824-20-5
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
780
DESCRIPTION
Amiprilose (SM 1213) has anti-inflammatory activity and inhibits the proliferation of a variety of hyperproliferative cell types.Amiprilose induces lymphokine-induced macrophage activation and may be used in studies of rheumatoid arthritis and psoriasis.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
ChEMBL Drugs
Drug Repurposing Hub
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
28
Molecular Weight
305.18
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
2
Aromatic Ring Count
0
cLogP
-0.45
TPSA
80.62
Fraction CSP3
1.0
Chiral centers
5.0
Largest ring
5.0
QED
0.62
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
MOA
CD antagonist
Pathway
Microbiology/virology
Source data
