General
Preferred name
VELNACRINE
Synonyms
HYDROXYTACRINE MALEATE ()
4-OH-TACRINE ()
VELNACRINE MALEATE ()
HP 029 maleate ()
Hydroxytacrine maleate (R,S) ()
Velnacrine (maleate) ()
HP 029 ()
Hydroxytacrine (maleate) ()
P-83-6029A ()
Mentane ()
P83 6029A ()
HP-029 ()
P-836029A ()
1-oh-tha ()
Velnacrina ()
1-hydroxytacrine ()
Hydroxytacrine ()
P&D ID
PD013190
CAS
124027-47-0
104675-29-8
112964-99-5
118909-22-1
Tags
available
drug candidate
drug
Drug indication
Cognitive impairment
Drug Status
approved
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Velnacrine maleate (HP 029) is an orally active cholinesterase inhibitor that can be used for the research of Alzheimer's disease[1].
PRICE
29
PRICE
32
DESCRIPTION
Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.
DESCRIPTION
Cholinesterase inhibitor
(LOPAC library)
DESCRIPTION
Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase (cholinesterase) inhibitor that enhances memory in rodents and may be used in the study of Alzheimer's dementia of the Alzheimer type (SDAT).
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
2
Compound Sets
13
Cayman Chemical Bioactives
ChEMBL Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
LOPAC library
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
51
Molecular Weight
214.11
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
2
cLogP
2.19
TPSA
59.14
Fraction CSP3
0.31
Chiral centers
1.0
Largest ring
6.0
QED
0.71
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Cholinesterase
Target
cholinesterase
Cholinesterase (ChE)
Pathway
Neuroscience
Neuronal Signaling
Source data
