General
Preferred name
ATRACURIUM
Synonyms
ATRACURIUM BESYLATE ()
Atracurium ()
CISATRACURIUM ()
BW-33A ()
51W89 ()
Tracrium ()
Atracurium (besylate) ()
BW 33A, 51W89 ()
BW 33A ()
NSC-760047 ()
atracurium besilate ()
Tracrium preservative free ()
Atracurium besylate preservative free ()
Atracurium dibesylate ()
Atracurium ion ()
Atracurium cation ()
P&D ID
PD013187
CAS
64228-81-5
64228-79-1
Tags
available
drug
Approved by
FDA
First approval
1983
Drug Status
approved
Drug indication
Anaesthesia
Neuromuscular Blocking Agent
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Atracurium (besylate) is a intermediate-duration non-depolarizing neuromuscular blocking agent, delivered by bolus injection in to a vein. It is a complex molecule with potential to exist as multiple stereoisomers.The INN for this drug stipulates the besylate salt, represented in PubChem CID 47320. We show the structure for the parent molecule, with no specified stereochemistry.
(GtoPdb)
DESCRIPTION
Atracurium Besylate is a neuromuscular blocking agent with ED95 of 0.2 mg/kg.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
22
AdooQ Bioactive Compound Library
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
Ki Database
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
57
Molecular Weight
928.51
Hydrogen Bond Acceptors
12
Hydrogen Bond Donors
0
Rotatable Bonds
24
Ring Count
6
Aromatic Ring Count
4
cLogP
8.07
TPSA
126.44
Fraction CSP3
0.51
Chiral centers
4.0
Largest ring
6.0
QED
0.04
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
nAChR
MOA
AChR
Therapeutic Class
Neuromuscular Nondepolarizing Agents
Source data
