General
Preferred name
metacycline
Synonyms
METHACYCLINE HYDROCHLORIDE ()
METHACYCLINE ()
Methacycline HCl ()
Rondomycin ()
Methacycline ()
Methacycline (hydrochloride) ()
NSC-356465 ()
NSC-757835 ()
Metacycline hydrochloride ()
MOTC ()
GS-2876 ()
Methacycline (hydrochloride) ()
P&D ID
PD013171
CAS
3963-95-9
914-00-1
Tags
natural product
drug
available
Approved by
FDA
Drug Status
investigational
approved
withdrawn
Max Phase
Phase 4
Drug indication
Antibacterial
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
3
Compound Sets
15
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
EU-OPENSCREEN Bioactive Compound Library
MedChem Express Bioactive Compound Library
NPC Screening Collection
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
46
Properties
(calculated by RDKit )
Molecular Weight
442.14
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
6
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
1
cLogP
-0.44
TPSA
181.62
Fraction CSP3
0.32
Chiral centers
5.0
Largest ring
6.0
QED
0.33
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Anti-infection
Target
16S ribosome
30S ribosome
antibiotic
Bacterial
Antibiotics
ATC
J01AA05
Source data
