General
Preferred name
NOMEGESTROL ACETATE
Synonyms
Nomegestrol (acetate) ()
Lutenyl ()
ORG 10486-0 ()
TX-066 ()
Zoely ()
TX 066 ()
ORG-10486-0 ()
P&D ID
PD013166
CAS
58652-20-3
Tags
natural product
drug
available
Approved by
EMA
First approval
2011
Drug Status
investigational
approved
Drug indication
Breast cancer
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
AdooQ Bioactive Compound Library
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
Natural product-based probes and drugs
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
370.21
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
4.19
TPSA
60.44
Fraction CSP3
0.7
Chiral centers
6.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Progesterone Receptor
PGR
Estrogen/progestogen Receptor
Indication
contraceptive
MOA
Progesterone receptor agonist
Biosynthetic Origin
Terpenoid (Steroid)
Therapeutic Indication
Contraception
Therapeutic Class
Hormone Therapy
Pathway
Vitamin D Related/Nuclear Receptor
Source data
