General
Preferred name
PIPERIDOLATE
Synonyms
PIPERIDOLATE HYDROCHLORIDE ()
Piperidolate (hydrochloride) ()
Crapinon ()
NSC-4349 ()
Dactil ()
Piperidolato ()
1087-A.N. ()
JB-305 ()
P&D ID
PD013164
CAS
129-77-1
82-98-4
Tags
available
drug candidate
drug
Drug Status
approved
experimental
investigational
Max Phase
2.0
Drug indication
Gastrointestinal disease
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Piperidolate hydrochloride is an antimuscarinic, inhibits intestinal cramp induced by acetylcholine (rats and dogs).
PRICE 34
DESCRIPTION Piperidolate is an antimuscarinic, inhibits intestinal cramp induced by acetylcholine (rats and dogs).
PRICE 29
DESCRIPTION The hydrochloride salt form of Piperidolate which is an antimuscarinic and could restrain the abnormal activity caused by acetylcholine. (BOC Sciences Bioactive Compounds)
DESCRIPTION Piperidolate hydrochloride is an antimuscarinic, could restrain the abnormal activity caused by acetylcholine. inhibits intestinal cramp induced by acetylcholine (rats and dogs). (TargetMol Bioactive Compound Library)
DESCRIPTION Piperidolate is a tertiary amine antimuscarinic. It is similar to atropine. It is mainly used in the smooth muscle spasm of the gastrointestinal tract and inhibits intestinal cramp induced by acetylcholine in rats and dogs. (BOC Sciences Bioactive Compounds)
DESCRIPTION Piperidolate inhibits intestinal cramp induced by acetylcholine (TargetMol Bioactive Compound Library)
Compound Sets
13
BOC Sciences Bioactive Compounds
piperidolate-hydrochloride-cas-129-77-1-item-56874
piperidolate-cas-82-98-4-item-136680
ChEMBL Drugs
CHEMBL1511957
CHEMBL1623992
DrugBank
DB13351
DrugCentral
2190
DrugCentral Approved Drugs
2190
DrugMatrix
Ki Database
Piperidolate
MedChem Express Bioactive Compound Library
HY-B0962
HY-B0962A
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
TargetMol Bioactive Compound Library
T7555
T7405
The Spectrum Collection
External IDs
38
Properties
(calculated by RDKit )
Molecular Weight
323.19
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
2
cLogP
3.85
TPSA
29.54
Fraction CSP3
0.38
Chiral centers
1.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
mAChR
muscarinic receptor
Pathway
Neuroscience
GPCR/G protein
Neuronal Signaling
Solubility
10 mM in H2O (free soluble)
Source data