General
Preferred name
RIMEXOLONE
Synonyms
Vexol ()
Rimexolon ()
ORG-6216 ()
Rimexolona ()
ORG 6216 ()
P&D ID
PD013160
CAS
49697-38-3
Tags
drug
available
Approved by
FDA
First approval
1994
Drug indication
Arthritis
Eye inflammation
Drug Status
approved
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Rimexolone is a corticosteroid.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
NPC Screening Collection
Prestwick Chemical Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
30
Molecular Weight
370.25
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
4.5
TPSA
54.37
Fraction CSP3
0.75
Chiral centers
8.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
anterior uveitis
Target
NR3C1, SERPINA6
MOA
Glucocorticoid Receptor agonist
Source data
