General
Preferred name
PRONETALOL
Synonyms
PRONETALOL HYDROCHLORIDE ()
Pronethalol hydrochloride ()
(¡À)-Pronethalo ()
(??)-Pronethalo ()
pronethalol ()
(±)-Pronethalo ()
PRONETALOLHYDROCHLORIDE ()
Inetol ()
AY-6204 HCL ()
Dl-pronethalol ()
GNF-Pf-2670 ()
Nethalide ()
AY 6204 [AS HYDROCHLORIDE] ()
ICI 38174 [AS HYDROCHLORIDE] ()
Naphthylisoproterenol ()
P&D ID
PD013154
CAS
54-80-8
51-02-5
325-16-6
Tags
natural product
drug
available
Drug Status
approved
withdrawn
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION β antagonist (Tocriscreen Total)
DESCRIPTION Pronethalol hydrochloride is a β-adrenergic antagonist. (BOC Sciences Bioactive Compounds)
Cell lines
0
Organisms
1
Compound Sets
13
BOC Sciences Bioactive Compounds
pronethalol-hydrochloride-cas-51-02-5-item-115099
ChEMBL Approved Drugs
CHEMBL16476
ChEMBL Drugs
CHEMBL16476
DrugCentral
2289
DrugCentral Approved Drugs
2289
DrugMatrix
MedChem Express Bioactive Compound Library
HY-B1238
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
The Spectrum Collection
Tocriscreen Total
Withdrawn 2.0
w54
External IDs
38
Properties
(calculated by RDKit )
Molecular Weight
229.15
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
2
cLogP
2.87
TPSA
32.26
Fraction CSP3
0.33
Chiral centers
1.0
Largest ring
6.0
QED
0.84
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
C
Toxicity type
carcinogenicity
Pathway
GPCR/G protein
Neuronal Signaling
Target
Adrenergic Receptor
Source data