General
Preferred name
naftidrofuryl
Synonyms
NAFRONYL OXALATE ()
Naftidrofurilo ()
NAFRONYL ()
Nafronyl oxalate salt ()
naftidrofuryl SR, Ethypharm ()
Naftidrofuryl (oxalate) ()
Naftidrofuryl oxalate ()
Praxilene ()
Naftidrofuryl hydrogen oxalate ()
Di-actane ()
Dusodril ()
LS-121 ()
Nafronyl acid oxalate ()
EU-1806 ()
NSC-225233 ()
Citoxid ()
Dubimax ()
Drosunal ()
Gevatran ()
P&D ID
PD013143
CAS
3200-06-4
31329-57-4
26263-44-5
Tags
available
drug candidate
drug
Drug indication
Cardiovascular disease
Cerebrovascular ischaemia
Drug Status
approved
experimental
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Naftidrofuryl oxalate (Nafronyl oxalate salt) is a drug used in the management of peripheral and cerebral vascular disorders as a vasodilator, enhance cellular oxidative capacity, and may also be a 5-HT2 receptor antagonist.
PRICE 29
DESCRIPTION Naftidrofuryl, being useful in enhancing cellular oxidative, could be used as a vasodilator in the treatment of peripheral and cerebral vascular disorders. (BOC Sciences Bioactive Compounds)
DESCRIPTION Naftidrofuryl oxalate is a 5-HT2 receptor antagonist. Naftidrofuryl is a peripheral vasodilator indicated in the treatment of chronic venous ulcers. (Enamine Bioactive Compounds)
DESCRIPTION Naftidrofuryl oxalate (Nafronyl oxalate) is a drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. It may also be an antagonist at 5HT-2 serotonin receptors. (TargetMol Bioactive Compound Library)
Compound Sets
16
BOC Sciences Bioactive Compounds
nafronyl-oxalate-cas-3200-06-4-item-337463
ChEMBL Drugs
CHEMBL1439099
CHEMBL1620794
DrugBank
DB13588
DrugCentral
1870
DrugCentral Approved Drugs
1870
DrugMAP
DMVMQ1L
DrugMAP Approved Drugs
DMVMQ1L
DrugMatrix
Enamine Bioactive Compounds
EBC-252067
MedChem Express Bioactive Compound Library
HY-B1107
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
nafronyl-oxalate-salt
TargetMol Bioactive Compound Library
T1081
The Spectrum Collection
External IDs
44
Properties
(calculated by RDKit )
Molecular Weight
383.25
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
10
Ring Count
3
Aromatic Ring Count
2
cLogP
4.45
TPSA
38.77
Fraction CSP3
0.54
Chiral centers
2.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
5-HT
5-HT Receptor
Pathway
GPCR/G protein
Neuronal Signaling
Neuroscience
Solubility
10 mM in H2O
Source data