General
Preferred name
AMPROLIUM
Synonyms
Amprolio ()
AMPROLIUM CHLORIDE ()
Amprovine ()
Amprolium HCl ()
Amprolium hydrochloride ()
Amprolium (hydrochloride) ()
AMPROLIUM ION ()
Amprol ()
Amprolsol ()
Thiacoccid ()
Anticoccid ()
NSC-755872 ()
NSC-523454 ()
Corid ()
Ampisol ()
Amprolium ()
P&D ID
PD013111
CAS
121-25-5
137-88-2
3053-18-7
13082-85-4
Tags
available
drug
drug candidate
Approved by
FDA
Drug Status
vet_approved
approved
experimental
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Amprolium, a thiamine derivative, could be commonly useful in poultry as a coccidiostat. (BOC Sciences Bioactive Compounds)
DESCRIPTION Amprolium Hydrochloride (Amprolium HCl) is a coccidiostat that interferes with thiamine metabolism. (TargetMol Bioactive Compound Library)
Compound Sets
15
AdooQ Bioactive Compound Library
A16410
BOC Sciences Bioactive Compounds
amprolium-cas-121-25-5-55769
Cayman Chemical Bioactives
25506
ChEMBL Drugs
CHEMBL1318296
CHEMBL1179735
Drug Repurposing Hub
DrugBank
DB11374
DrugBank Approved Drugs
DB11374
DrugCentral
5557
MedChem Express Bioactive Compound Library
HY-B0937A
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
amprolium-hcl
TargetMol Bioactive Compound Library
T0872L
The Spectrum Collection
External IDs
59
Properties
(calculated by RDKit )
Molecular Weight
243.16
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
2
cLogP
1.66
TPSA
55.68
Fraction CSP3
0.36
Chiral centers
0.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Parasite
Vitamin
Pathway
Anti-infection
Microbiology/virology
Indication
coccidiosis
MOA
thiamine uptake blocker
Solubility
Soluble in Water
Source data