General
Preferred name
TULOBUTEROL
Synonyms
TULOBUTEROL HYDROCHLORIDE ()
Berachin ()
Hokunalin ()
tulobuterol (patch) ()
Tulobuterol (hydrochloride) ()
C-78 (free base) ()
C-78 ()
Bremax ()
Tulobuterol HCl ()
Chlibamol ()
Atenos ()
NSC-758643 ()
Respacal ()
Lobuterol ()
Brelomax ()
P&D ID
PD013098
CAS
41570-61-0
56776-01-3
Tags
available
drug
Drug Status
approved
investigational
Max Phase
2.0
Drug indication
Airway obstruction
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Tulobuterol hydrochloride (C-78) is a long-acting ¦Â2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength[1]. Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation[2].
PRICE 29
DESCRIPTION Tulobuterol (C-78 free base) is a long-acting ¦Â2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength[1].
DESCRIPTION beta-Adrenoceptor agonist related to structurally to terbutaline; bronchodilator (LOPAC library)
DESCRIPTION Tulobuterol hydrochloride is a salt form of Tulobuterol, which is a long-acting beta2-adrenergic receptor agonist. (BOC Sciences Bioactive Compounds)
DESCRIPTION Tulobuterol hydrochloride (Hokunalin) is a long-acting beta2-adrenergic receptor agonist. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
17
AdooQ Bioactive Compound Library
A13432
BOC Sciences Bioactive Compounds
tulobuterol-hydrochloride-cas-56776-01-3-item-71835
Cayman Chemical Bioactives
35562
ChEMBL Drugs
CHEMBL1159717
DrugBank
DB12248
DrugCentral
2782
DrugCentral Approved Drugs
2782
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
EOS100025
LOPAC library
MedChem Express Bioactive Compound Library
HY-W011733
HY-B1810
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
tulobuterol-hydrochloride
TargetMol Bioactive Compound Library
T3277
The Spectrum Collection
External IDs
46
Properties
(calculated by RDKit )
Molecular Weight
227.11
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
2.76
TPSA
32.26
Fraction CSP3
0.5
Chiral centers
1.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
beta
Target
Adrenergic Receptor
antibiotic
Influenza Virus
β2-adrenergic receptor
Androgen Receptor
Pathway
GPCR/G protein
Microbiology/virology
Neuroscience
Neuronal Signaling
Anti-infection
Solubility
In Vitro:<br/>DMSO : ≥ 100 mg/mL (378.52 mM)
Source data