General
Preferred name
NIFEKALANT
Synonyms
Nifekalant (hydrochloride) ()
Nifekalant hydrochloriden/a ()
MS-551 ()
Nifekalant hydrochloride ()
P&D ID
PD013077
CAS
130636-43-0
130656-51-8
Tags
available
drug
Drug Status
investigational
approved
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
39
Properties
(calculated by RDKit )
Molecular Weight
405.2
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
2
Rotatable Bonds
11
Ring Count
2
Aromatic Ring Count
2
cLogP
0.33
TPSA
122.64
Fraction CSP3
0.47
Chiral centers
0.0
Largest ring
6.0
QED
0.41
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
member
MOA
Potassium Channel Blockers
K(V)11.1 (erg1) Channel Blockers
potassium channel blocker
Indication
ventricular arrhythmias, ventricular tachycardia (VT)
Pathway
Membrane Transporter/Ion Channel
Target
Potassium Channel
Source data
